diabetes

Beneficial Effects of Vitamin E in Diabetic Wound Healing

In diabetic condition, wound healing may be impaired or delayed due to high reactive oxygen species (ROS) and low antioxidant levels.
Vitamin E is an antioxidant which exerts both systemic and topical effects. The effects of vitamin E on wound healing remains controversial.
Numerous studies have been carried out to observe the ability of vitamin E in modulating signal transduction and gene expression.
However, the detailed molecular mechanisms are not yet clear. Vitamin E may promote healing by supressing ROS generation

Role of Oxidative Stress in Diabetic Wound Healing

Wound healing is a complex process which involves homeostasis, inflammation, proliferation and maturation and remodelling. These
four phases occur in a proper sequence and duration of time. Most wounds heal without difficulty. However, some wounds will not heal
properly due to the presence of factors that impair wound healing. Wounds that did not heal well may become chronic and non-healing.
In diabetic condition, wound healing may be impaired or delayed due to high reactive oxygen species (ROS) and low antioxidant levels

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