Antioxidant

Effect of Palm Tocotrienol Rich Fraction on Oxidative Status of Heart in a Rat Model of Isoprenaline-Induced Myocardial Injury

Background: Palm oil tocotrienol rich fraction (TRF) has shown potential as a cardioprotective, antioxidant, anti-inflammation, anti-ageing as well as anticancer agent through inhibiting free radical production and enhancing the antioxidant enzyme activity. Therefore, this study aimed to identify the effect of palm TRF on oxidative status in isoprenaline-induced myocardial injury in rats.

Beneficial Effects of Vitamin E in Diabetic Wound Healing

In diabetic condition, wound healing may be impaired or delayed due to high reactive oxygen species (ROS) and low antioxidant levels.
Vitamin E is an antioxidant which exerts both systemic and topical effects. The effects of vitamin E on wound healing remains controversial.
Numerous studies have been carried out to observe the ability of vitamin E in modulating signal transduction and gene expression.
However, the detailed molecular mechanisms are not yet clear. Vitamin E may promote healing by supressing ROS generation

Tocotrienol Rich Fraction Modulates the Expression of Synaptogenic RNAs in Neurons of Caenorhabditis Elegans

Background: One of the main concerns of getting older is the experience of impairments in memory function. Synapses play an important role in learning and memory during aging and their deterioration is associated with reactive oxygen species. Among the many vitamin E analogues, tocotrienols are known to have neuroprotective effect as well as remarkable antioxidant activities. Recent in vitro studies have successfully extracted embryos from C. elegans to develop neurons, muscles and epithelial cells.

Role of Oxidative Stress in Diabetic Wound Healing

Wound healing is a complex process which involves homeostasis, inflammation, proliferation and maturation and remodelling. These
four phases occur in a proper sequence and duration of time. Most wounds heal without difficulty. However, some wounds will not heal
properly due to the presence of factors that impair wound healing. Wounds that did not heal well may become chronic and non-healing.
In diabetic condition, wound healing may be impaired or delayed due to high reactive oxygen species (ROS) and low antioxidant levels

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