Research Articles

Combined effects of Eurycoma longifolia and Calcium on Bone Metabolism of Orchidectomised Male Rats

Background: Osteoporosis is characterized by low bone mass and destruction of bone microarchitecture. Androgen deficiency or hypogonadism is one of the major risk factors of osteoporosis in men. Testosterone replacement therapy (TRT) is the main treatment for hypogonadal osteoporosis but may cause side effects such as prostate cancer and cardiovascular diseases. An alternative treatment is required, with similar efficacy but minimal side effects.

3rd International Conference on Advances in Medical Science (ICAMS) 2017

Embalming for Medical Education: A Single Approach Using a Simple Solution

Method for preserving human body for medical education has seen minimal change over the years. Since the discovery of preserving
the cadavers, the technique only evolves around the site of delivery and the embalming fluid used. Despite the advancement in medical
education technology, the human cadaver is still the preferred choice for teaching the students in anatomy related courses. However,
the topic of embalming is less discussed in the article journal lately. One possible explanation is that it could probably reaches its perfection


Hidden Dangers In The Blue Ocean

Incidences of marine sting envenoming in Sabah is on the rise. It has resulted in deaths and sufferings involving both local and visitors.
There is an urgent need to increase the awareness on marine envenoming and poisoning and to train healthcare providers on the management
of marine sting envenoming cases. A Marine Envenoming and Poisoning (MEP) course was conducted in Sabah in 2015. Fifty
-eight out of the total 63 participants who had attended this course submitted their feedback. This activity was found to improve competence

Tocotrienol Rich Fraction Modulates the Expression of Synaptogenic RNAs in Neurons of Caenorhabditis Elegans

Background: One of the main concerns of getting older is the experience of impairments in memory function. Synapses play an important role in learning and memory during aging and their deterioration is associated with reactive oxygen species. Among the many vitamin E analogues, tocotrienols are known to have neuroprotective effect as well as remarkable antioxidant activities. Recent in vitro studies have successfully extracted embryos from C. elegans to develop neurons, muscles and epithelial cells.

Bone Analysis of Young Adult Rabbit Femur via Micro-Computed Tomography

Micro-computed tomography is a useful tool for bone evaluation as various parameters are readily available. It has been widely used especially in small animal imaging for preclinical investigation. The Skyscan 1176 is one of the micro-computed tomography systems available that provide high performance scanning. The purpose of this paper is to provide a reference document for basic steps utilising Skyscan 1176 for ex-vivo young adult rabbit femur and similar sample.

An Inventory Approach to Humanizing Work and Working Environment in Indian Underground Coal Mines

Reporting of productivity alteration due to environmental stress on face drillers (FD) in India is scarce. In this study the heat strain of twenty healthy FD was evaluated during their actual work at varying depth of working. Working heart rates (WHR) were measured for all the participants and compared between two groups of miners from Mine A and Mine B. Environmental data was collected throughout the shift. Mean Working Heart Rate (WHR) was 141-148 beats/min and 139-145 beats/min for Mine A and Mine B FD respectively.

Clinical Skills Teaching in Preclinical Years

Clinical Skill Learning (CSL) is a new module which was introduced in 2005/2006 session of the Universiti Kebangsaan Malaysia (UKM) Faculty of Medicine medical undergraduate curriculum. The CSL module allows early exposure of  clinical skills and experience to preclinical year students to increase their confidence level when they enter clinical years. The module also  promote their understanding on the clinical applications of medical sciences subjects, thus boosting their interest to study.

The Suitable Androgen-Deficient Models for Investigation of Eurycoma Longifolia, A Pro-Androgenic Agent

There are several androgen deficiency models that can be used to study the effects of pro-androgenic agents such as Eurycoma longifolia (EL). Suitable model must be chosen so that the androgenic effects of the agents tested could be demonstrated. As an example, EL was postulated to produce androgenic effects by stimulating the testosterone release by the testes. This makes the orchidectomy rat model of androgen deficiency unsuitable because EL cannot act with the removal of both testes.


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